Perphenazine, Antipsychotic agent (TBI4709)

Description

Product Details

Formal Name: 2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol

Molecular Formula: C₂₁H₂₆ClN₃OS

Formula Weight: 403.98

CAS Number: 58-39-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

 

Applications

Antipsychotic agent

 

Functions

Perphenazine is a clinically useful typical antipsychotic drug.  The therapeutic mode of action is not well understood but it binds to a wide variety of receptors including serotonin, histamine, dopamine, and α-adrenergic. Perphenazine is an inhibitor of acid sphingomyelinase(ASM) and positively effected  xenografted tumor growth via perturbation of intracellular cholesterol transport through ASM.  It has also been shown to be an inhibitor of glutamate dehydrogenase.

 

Application Procedures

First dissolved in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Additional information

SIZE (mg)	250 MG, 100 MG

TBI4709_Perphenazine