PD-325901, MEK inhibitor (TBI2161)
$99.00 – $369.00
MEK inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2161-5MG | Yes | 5 MG | $99.00 | |||
TBI2161-25MG | Yes | 25 MG | $369.00 |
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Description
Product Details
Formal Name: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide
Molecular Formula: C16H14F3IN2O4
Formula Weight: 482.20
CAS Number: 391210-10-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 12 mg/ml)
Storage: RT
Stability: ≥ 1 year.
Applications
MEK inhibitor
Functions
A selective non-ATP competitive MEK inhibitor (IC50 = 0.33 nM). Inhibits growth and/or proliferation of a variety of cancer cells. Enhances self-renewal of embryonic stem cells. In combination with vitamin C, synergistically induces hypomethylation of mouse embryonic stem cells. In combination with CHIR-99021 and A83-01 induces generation of ground state iPS cells from human and rat somatic cells.
Application Procedures
First dissolved in DMSO (up to 12 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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