PD 123319 ditrifluoroacetate, Angiotensin II type II antagonist (TBI4959)
$135.00 – $450.00
Angiotensin II type II antagonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4959-5MG | Yes | 5 MG | $135.00 | |||
TBI4959-25MG | Yes | 25 MG | $450.00 |
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Description
Product Details
Formal Name: (6S)-1-[[4-(Dimethylamino)-3-methylphenylmethyl]-5-(2,2diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acid ditrifluoroacetate
Molecular Formula: C31H32N4O3·2CF3CO2H
Formula Weight: 736.70
CAS Number: 136676-91-0
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or Water (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Angiotensin II type II antagonist
Functions
Potent (IC50 = 34 nM) and selective non-peptide angiotensin II type 2 (AT2) antagonist. Ameliorated symptoms of 2,4-dinitrobenzenesulfonic-induced colitis in rats via inhibition of NF-kB activation. PD123319 displayed protective effects in ischemia-reperfusion injury and oxidative damage in rat hearts.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or Water (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or water may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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