Optovin, TRPA1 channel activator (TBI1456)
$126.00 – $504.00
TRPA1 channel activator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1456-5MG | Yes | 5 MG | $126.00 | |||
TBI1456-25MG | Yes | 25 MG | $504.00 |
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Description
Product Details
Formal Name: 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone
Molecular Formula: C15H13N3OS2
Formula Weight: 315.41
CAS Number: 348575-88-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
TRPA1 channel activator
Functions
Reversible, photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM) and mice, in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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