Oltipraz, Nrf2 activator (TBI2831)
$70.00 – $281.00
Nrf2 activator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2831-50MG | Yes | 50 MG | $70.00 | |||
TBI2831-250MG | Yes | 250 MG | $281.00 |
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Description
Product Details
Formal Name: 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione
Molecular Formula: C8H6N2S3
Formula Weight: 226.34
CAS Number: 64224-21-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Nrf2 activator
Functions
Upregulates the transcription factor NRF2 and prevents insulin resistance and obesity induced by high fat diet in C57BL/6J mice. Attenuates the progression of fibrosis in a rat model of nonalcoholic steatohepatitis. Attenuates chronic hypoxia-induced cardiopulmonary alterations in mice. Promotes liver regeneration after partial hepatectomy. Off target effects: Activates constitutive androstane receptor (CAR).
Application Procedures
First dissolved in DMSO (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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