NVP-BGJ398, Pan-specific FGFR inhibitor (TBI4817)
$117.00 – $369.00
Pan-specific FGFR inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4817-10MG | Yes | 10 MG | $117.00 | |||
TBI4817-50MG | Yes | 50 MG | $369.00 |
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Description
Product Details
Formal Name: 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)-1-methylurea
Alternate Names: Infigratinib
Molecular Formula: C26H31Cl2N7O3
Formula Weight: 560.48
CAS Number: 872511-34-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 5 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Pan-specific FGFR inhibitor
Functions
NVP-BGJ398 is a potent and selective pan-FGFR inhibitor (IC50 = 0.9nM, 1.4 nM, 1.0 nM, and 60 nM for FGFR1,2,3,4 respectively). It has also been used in a mouse model of Achondroplasia (most common form of dwarfism) to correct pathological hallmarks of this condition.
Application Procedures
First dissolved in DMSO (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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