Nutlin-3, p53/mdm2 inhibitor (TBI1350)
$180.00 – $720.00
p53/mdm2 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1350-5MG | Yes | 5 MG | $180.00 | |||
TBI1350-25MG | Yes | 25 MG | $720.00 |
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Description
Product Details
Formal Name: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one
Molecular Formula: C30H30Cl2N4O4
Formula Weight: 581.51
CAS Number: 548472-68-0
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
p53/mdm2 inhibitor
Functions
MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p53. Displays antiproliferative activity and induces apoptosis in a variety of tumor cells.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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