Nelfinavir mesylate, HIV protease inhibitor (TBI3050)
$108.00 – $378.00
HIV protease inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3050-10MG | Yes | 10 MG | $108.00 | |||
TBI3050-50MG | Yes | 50 MG | $378.00 |
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Description
Product Details
Formal Name: (3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide methanesulfonate
Alternate Names: AG-1343
Molecular Formula: C32H45N3O4S • CH3SO3H
Formula Weight: 663.9
CAS Number: 159989-65-8
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 70 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
HIV protease inhibitor
Functions
Nelfinavir is a clinically useful anti-HIV agent acting via inhibition of HIV-1 protease (Ki=2 nM). It also displays efficacy in cancer, malaria, tuberculosis and SARS. Displays broad spectrum anticancer activity and induces endoplasmic reticulum stress, autophagy and apoptosis in vitro and in vivo. Inhibits the growth of HER2-positive breast cancer cells via inhibition of HSP90 through a novel mechanism. Weak inhibition of receptor tyrosine protein kinases may also contribute to its anti-cancer effect.
Application Procedures
First dissolved in DMSO (up to 70 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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