ML-204, TRPC4 blocker (TBI2841)

Description

Product Details

Formal Name: 4-Methyl-2-(1-piperidinyl)quinoline

Molecular Formula: C₁₅H₁₈N₂

Formula Weight: 226.32

CAS Number: 5485-86-1

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 20 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

 

Applications

TRPC4 blocker

 

Functions

Selective blocker of TRPC4 channels (IC50 = 0.96 – 2.6 μM, depending on assay). Displays 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5.  Has no significant activity at TRPV1, TRPV3, TRPA1 and TRPM8 channels at concentrations up to 22 μM. A useful tool for exploring the involvement of TRPC and TRPC-like channels in cellular signaling and physiology.

 

Application Procedures

First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Additional information

SIZE (mg)	25 MG, 5 MG

Datasheet:

TBI2841_ML-204

MSDS:

TBI2841_ML-204_MSDS_2024