Leptomycin B, Nuclear export inhibitor (TBI2084)

$108.00$432.00

Nuclear export inhibitor

SKU: TBI2084 Category:
SKUStock SIZE (mg) PriceQuantity
TBI2084-200UG Yes 200 µg $108.00
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TBI2084-1MG Yes 1 MG $432.00
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Description

Product Details

Molecular Formula: C33H48O6

Formula Weight: 540.75

CAS Number: 87081-35-4

Purity: >98%

Formulation: Soln in ethanol

Solubility: Supplied in solution in ethanol (1 mg/ml).  Further dilutions may be made with either ethanol or DMSO.

Storage: -20°C

Stability: ≥ 1 year.

 

Applications

Nuclear export inhibitor

 

Functions

Inhibitor of nuclear export of proteins. Acts via covalent binding to and inhibiting CRM1/exportin-11. Inhibits the nuclear export of the HIV regulatory protein Rev2. Stabilizes p53 by blocking its nuclear export3.

 

Application Procedures

Solutions in DMSO are unstable and must be used within one working day. Do not store DMSO solutions.

Additional information

SIZE (mg)

1 MG, 200 µg

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