ISO-1, Macrophage migration inhibitory factor (MIF) antagonist (TBI1185)
$108.00 – $396.00
Macrophage migration inhibitory factor (MIF) antagonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1185-5MG | Yes | 5 MG | $108.00 | |||
TBI1185-25MG | Yes | 25 MG | $396.00 |
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Description
Product Details
Formal Name: (S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl ester
Molecular Formula: C12H13NO4
Formula Weight: 235.24
CAS Number: 478336-92-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Macrophage migration inhibitory factor (MIF) antagonist
Functions
Antagonist of macrophage migration inhibitory factor (MIF, a pro-inflammatory cytokine). Displays anti-inflammatory activity. Increases survival in severe sepsis. Inhibits airway remodeling in mouse asthma model. Blocks MIF-induced autophagy. Active in cellular and mouse models.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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