IM156, AMPK activator/Mitochondrial protein complex I inhibitor (TBI4657)
$108.00 – $351.00
AMPK activator/Mitochondrial protein complex I inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4657-5MG | Yes | 5 MG | $108.00 | |||
TBI4657-25MG | Yes | 25 MG | $351.00 |
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Description
Product Details
Formal Name: N’-[N’-[4-(Trifluoromethoxy)phenyl]carbamimidoyl]pyrrolidine-1-carboxamidine
Alternate Names: HL156A
Molecular Formula: C13H16F3N5O
Formula Weight: 315.30
CAS Number: 1422365-93-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
AMPK activator/Mitochondrial protein complex I inhibitor
Functions
Potent activator of AMP-activated protein kinase (AMPK) showing greater activity than metformin or AICAR. It displayed protective effects in vivo against peritoneal, liver, renal, and pulmonary fibrosis. IM156 induces metabolic stress in Myc+ lymphoma cells by inhibiting TCA cycle metabolism and mitochondrial respiration (inhibits mitochondrial protein complex 1). IM156 acts as an antiproliferative in several cancer models.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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