Honokiol, SIRT3 activator (TBI2311)
$99.00 – $396.00
SIRT3 activator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2311-10MG | Yes | 10 MG | $99.00 | |||
TBI2311-50MG | Yes | 50 MG | $396.00 |
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Description
Product Details
Formal Name: 3′,5-Diallyl-[1,1′-biphenyl]-2,4′-diol
Alternate Names: NSC-293100
Molecular Formula: C18H18O2
Formula Weight: 266.30
CAS Number: 35354-74-6
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
SIRT3 activator
Functions
Natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production in wild type but not SIRT3-KO cells. It reversed cardiac hypertrophy in mice and rescued myocardial and mitochondrial energetics in type 2 diabetic rats. It was shown to increase SIRT3 expression in the hippocampus and attenuated surgery-induced memory loss, neuronal apoptosis, neuroinflammation and oxidative damage. It increases expression of adipocyte gene markers, gene-involved lipolysis and glucose transport and in general, promotes insulin sensitivity.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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