GW-501516, PPARd agonist (TBI1542)
$99.00 – $342.00
PPARd agonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1542-5MG | Yes | 5 MG | $99.00 | |||
TBI1542-25MG | Yes | 25 MG | $342.00 |
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Description
Product Details
Formal Name: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazoyl]methyl]thio]phenoxy]acetic acid
Molecular Formula: C21H18F3NO3S2
Formula Weight: 453.50
CAS Number: 317318-70-0
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 20 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
PPARd agonist
Functions
Potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes. Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves hematopoietic stem cell maintenance. Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation. Upregulates human Sirt1 via Sp1 activation. Along with exercise, GW-501516 synergistically increases running endurance.
Application Procedures
First dissolved in DMSO (up to 40 mg/ml) or in Ethanol (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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