GS-441524, Remdesivir active metabolite (TBI4485)
$81.00 – $261.00
Remdesivir active metabolite
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4485-5MG | Yes | 5 MG | $81.00 | |||
TBI4485-25MG | Yes | 25 MG | $261.00 |
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Description
Product Details
Formal Name: (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
Molecular Formula: C12H13N5O4
Formula Weight: 291.30
CAS Number: 1191237-69-0
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Remdesivir active metabolite
Functions
Developed as an antiviral, with activity against HCV, YFV, DENV-2, influenza A, parainfluenza 3, and SARS-CoV. Also shown to be effective for feline infectious peritonitis. Notably the COVID-19 drug Remdesivir is rapidly metabolized in human serum to GS-441524, which shows comparable efficacy against SARS-CoV-2 in vitro, may reach the lungs more effectively, and has a better toxicity profile.
Application Procedures
First dissolved in DMSO (25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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