Fingolimod (FTY-720), S1P 1/3 receptor agonist (TBI2138)
$81.00 – $306.00
S1P 1/3 receptor agonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2138-50MG | Yes | 50 MG | $81.00 | |||
TBI2138-250MG | Yes | 250 MG | $306.00 |
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Description
Product Details
Formal Name: 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol hydrochloride
Alternate Names: Fingolimod
Molecular Formula: C19H33NO2 · HCl
Formula Weight: 343.94
CAS Number: 162359-56-0
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
Storage: -20°C
Stability: ≥ 1 year.
Applications
S1P 1/3 receptor agonist
Functions
An analog of sphingosine which, when taken up into cells, is phosphorylated and acts as an agonist at sphingosine-1-phosphate receptors (S1P1/3). Potently inhibits regulatory T cell proliferation in vitro and in vivo. Enhances microvascular remodeling via expansion of arterioles and capillary networks. Potent immunomodulatory, down-regulating microglial cell inflammation. Clinically effective agent for relapsing forms of multiple sclerosis. Stimulates neuronal gene expression, axonal growth and regeneration.
Application Procedures
First dissolved in DMSO (up to 100 mg/ml) or in Ethanol (up to 40 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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