Fasudil HCl, ROCK inhibitor (TBI2137)
$94.00 – $279.00
ROCK inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2137-50MG | Yes | 50 MG | $94.00 | |||
TBI2137-250MG | Yes | 250 MG | $279.00 |
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Description
Product Details
Formal Name: 1-(5-Isoquinolinesulfonyl)homopiperazine HCl
Alternate Names: HA-1077
Molecular Formula: C14H17N3O2S · HCl
Formula Weight: 327.84
CAS Number: 105628-07-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
ROCK inhibitor
Functions
Rho-associated kinase inhibitor (IC50 = 1.9 µM and 10.7 µM for Rho-associated kinase II and Rho-associated kinase respectively). Inhibits other kinases including cyclic nucleotide-dependent protein kinases. Reduces tryptamine-evoked vasopressor responses. attenuates bleomycin-induced pulmonary fibrosis in a mouse model. Clinically useful vasodilator.
Application Procedures
First dissolved in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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