Erastin, Ferroptosis inducer (TBI3406)
$117.00 – $468.00
Ferroptosis inducer
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI3406-5MG | Yes | 5 MG | $117.00 | |||
TBI3406-25MG | Yes | 25 MG | $468.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: 2-[1-[4-[2-(4-Chlorophenyoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
Molecular Formula: C30H31ClN4O4
Formula Weight: 547.04
CAS Number: 571203-78-6
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml with warming).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Ferroptosis inducer
Functions
Ferroptosis inducer. Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress response. Inhibition of system Xc- leads to cysteine starvation, glutathione depletion and induction of ferroptosis. Also blocks mitochondrial voltage-dependent anion channels (specifically VDAC2 and 3).
Application Procedures
First dissolved in DMSO (up to 10 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “Erastin, Ferroptosis inducer (TBI3406)”
You must be logged in to post a review.
Reviews
There are no reviews yet.