DY-131, Estrogen receptor ERRb and ERRg agonist (TBI1561)
$90.00 – $324.00
Estrogen receptor ERRb and ERRg agonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1561-5MG | Yes | 5 MG | $90.00 | |||
TBI1561-25MG | Yes | 25 MG | $324.00 |
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Description
Product Details
Formal Name: N-(4-(Diethylaminobenzylidenyl)-N’-(4-hydroxybenzoyl)-hydrazine
Alternate Names: GSK-9089
Molecular Formula: C18H21N3O2
Formula Weight: 311.38
CAS Number: 95167-41-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 8 mg/ml with warming)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Estrogen receptor ERRb and ERRg agonist
Functions
Selective agonist at estrogen-related receptors ERRβ and ERRɣ with minimal activity at ERRα, ERα and ERβ at concentrations up to 30 μM. Displays antiproliferative activity in prostate cancer cells. Promotes hormone production and cell fusion in cytotrophoblasts. In breast cancer cells DY131 arrests cells in G2/M and causes mitotic spindle defects. Inhibits osteoclastogenesis and protects against inflammatory bone loss induced by LPS in vivo.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml) or in Ethanol (up to 8 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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