Domoic acid, Marine natural product neurotoxin (TBI2472)
$288.00
Marine natural product neurotoxin
SKU | Stock | SIZE | Price | Quantity | ||
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TBI2472-50UG | Yes | 50 µg | $288.00 |
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Description
Product Details
Formal Name: (2S,3S,4S)-2-Carboxy-4-[(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadien-1-yl]-3-pyrrolidineacetic acid
Molecular Formula: C15H21NO6
Formula Weight: 311.30
CAS Number: 14277-97-5
Purity: >97%
Formulation: Soln in water with 5% acetonitrile at 50 µg / 0.5 ml
Solubility: Soluble in Water
Storage: -20°C
Stability: ≥ 2 years.
Applications
Marine natural product neurotoxin
Functions
Domoic acid (DA), a kainic acid-type neurotoxin produced by certain species of the marine pennate diatom Pseudo-nitzschia is responsible for amnesic shellfish poisoning. Suspension feeders such as bivalve mollusks can accumulate and retain high amounts of DA in their tissues, threatening human health. DA is a potent agonist at kainate and AMPA receptors and induces convulsive behavior and seizures in rodents. It induces structural and molecular changes in the developing zebra fish nervous system.
Application Procedures
First dissolved in Water, then diluted to aqueous buffer.
Additional information
SIZE | 50 µg |
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