DC260126, GPR40 antagonist(TBI1531)
$86.00 – $279.00
GPR40 antagonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1531-5MG | Yes | 5 MG | $86.00 | |||
TBI1531-25MG | Yes | 25 MG | $279.00 |
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Description
Product Details
Formal Name: N-(4-Butylphenyl)-4-fluorobenzenesulfonamide
Molecular Formula: C16H18NO2S
Formula Weight: 307.37
CAS Number: 346692-04-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 80 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
GPR40 antagonist
Functions
A GPR40 receptor antagonist. Suppresses fatty acid-induced elevation of intracellular Ca++. Inhibits palmitic acid potentiated glucose–stimulated insulin secretion in Min6 pancreatic β cells in vitro. Lowers serum insulin levels, increases insulin sensitivity2 in obese Zucker rats (6 mg/kg). Reduces pancreatic β cell apoptosis in obese diabetic (db/db) rats. Protects Min6 β cells from palmitic acid-induced ER stress and apoptosis.
Application Procedures
First dissolved in DMSO (up to 80 mg/ml) or in Ethanol (up to 80 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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