Darunavir, HIV-1 protease inhibitor (TBI4930)
$108.00 – $360.00
HIV-1 protease inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4930-10MG | Yes | 10 MG | $108.00 | |||
TBI4930-50MG | Yes | 50 MG | $360.00 |
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Description
Product Details
Formal Name: [(3aS,4R,6aR)-2,3,3a,5,6a-Hexahydrofuro[2,3-b]furan-4-yl] N-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
Alternate Names: UIC-94017; TMC114
Molecular Formula: C27H37N3O7S
Formula Weight: 657.70
CAS Number: 206361-99-1
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
HIV-1 protease inhibitor
Functions
Darunavir is a very potent (IC50 = 3 nM against lab HIV-1 strains and clinical isolates) HIV-1 protease inhibitor that is in clinical use. Also potent against multi-PI-resistant HIV-1 strains from patient samples. Darunavir has been investigated as a potential anti-SARS-CoV2 therapeutic with mixed results.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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