Cinnabarinic acid, AhR ligand, endogenous (TBI2883)
$90.00 – $356.00
AhR ligand, endogenous
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2883-5MG | Yes | 5 MG | $90.00 | |||
TBI2883-25MG | Yes | 25 MG | $356.00 |
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Description
Product Details
Formal Name: 2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid
Alternate Names: Cinnabaric acid
Molecular Formula: C14H8N2O6
Formula Weight: 300.22
CAS Number: 606-59-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
AhR ligand, endogenous
Functions
A novel endogenous tryptophan metabolite which acts as an aryl hydrocarbon receptor (AHR) agonist. It drives IL-22 production by stimulating the differentiation of human and mouse T cells producing IL-22. Induces apoptosis in thymocytes. Activates type 4 metabotropic glutamate receptors. Counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells. Displays neuroprotective activity.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml) or in DMF (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or DMF may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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