CH-223191, Arylhydrocarbon receptor antagonist (TBI3089)
$90.00 – $351.00
Arylhydrocarbon receptor antagonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI3089-5MG | Yes | 5 MG | $90.00 | |||
TBI3089-25MG | Yes | 25 MG | $351.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl]-1H-pyrazole-5-carboxamide
Molecular Formula: C19H19N5O
Formula Weight: 333.39
CAS Number: 301326-22-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Arylhydrocarbon receptor antagonist
Functions
Arylhydrocarbon (AhR) receptor antagonist, IC50=30 nM. Blocks endogenous AhR agonist-induced differentiation of Th17 cells. Promotes expansion of human hematopoietic stem cells. Mitigates cytokine-mediated inflammatory signaling in human fibroblast-like synoviocytes. An important tool for probing the involvement of AhR in the toxicity of various environmental toxins such as TCDD and other dioxins.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “CH-223191, Arylhydrocarbon receptor antagonist (TBI3089)”
You must be logged in to post a review.
Reviews
There are no reviews yet.