BML-111, LXA agonist; Antiinflammatory ativity (TBI3202)
$90.00 – $360.00
LXA agonist; Antiinflammatory ativity
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3202-5MG | Yes | 5 MG | $90.00 | |||
TBI3202-25MG | Yes | 25 MG | $360.00 |
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Description
Product Details
Formal Name: (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate
Molecular Formula: C8H16O5
Formula Weight: 192.21
CAS Number: 78606-80-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
LXA agonist; Antiinflammatory ativity
Functions
A novel truncated analog of lipoxin A4 which retains anti-inflammatory activity.1 Inhibits LTB4-induced leukocyte chemotaxis, IC50=5 nM). Attenuates hemorrhagic shock-induced acute lung injury in a rat model. Displays hepatoprotective effects in acetaminophen-induced liver injury in mice. Limits inflammatory damage in the cerebral cortex and helps maintain blood brain barrier integrity in a rat model of ischemic stroke. Attenuates renal ischemia/reperfusion injury via activation of p38 MAPK/PPARα/HO-1 pathway.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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