Auranofin, IKK inhibitor (TBI2373)
$90.00
IKK inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2373-50MG | Yes | 50 MG | $90.00 |
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Description
Product Details
Formal Name: 1-Thio-ß-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate
Alternate Names: SKF-39162
Molecular Formula: C20H34AuO9PS
Formula Weight: 678.49
CAS Number: 34031-32-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 4 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
IKK inhibitor
Functions
Disease-modifying antirheumatic drug (DMARD). Potent inhibitor of selenoenzyme thioredoxin reductase and IκB kinase (IKK) by modifying Cys-179. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions.
Application Procedures
First dissolved in DMSO (up to 5 mg/ml) or in Ethanol (up to 4 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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