Atglistatin, ATGL inhibitor (TBI4598)
$108.00 – $405.00
ATGL inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4598-5MG | Yes | 5 MG | $108.00 | |||
TBI4598-25MG | Yes | 25 MG | $405.00 |
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Description
Product Details
Formal Name: N’-[4’-(Dimethylamino)[1,1’-biphenyl]-3-yl]-N,N,-dimethylurea
Molecular Formula: C17H21N3O
Formula Weight: 283.37
CAS Number: 1469924-27-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
Storage: -20°C
Stability: ≥ 2 years.
Applications
ATGL inhibitor
Functions
Atglistatin is the first small molecule inhibitor of adipose triglyceride lipase (ATGL) – IC50 = 700 nM. It exhibits high selectivity for ATGL, is active in vitro and in vivo, and does not inhibit other key metabolic lipases. ATGL is the rate limiting enzyme in lipolysis and is thus an excellent target to reduce fatty acid mobilization and decrease lipotoxicity in metabolic syndrome. Inhibition of ATGL may be a useful strategy to attack the increased metabolic rate of cancerous cells.
Application Procedures
First dissolved in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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