AM-580, Retinoid RARα agonist (TBI5511)
$126.00 – $360.00
Retinoid RARα agonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI5511-5MG | Yes | 5 MG | $126.00 | |||
TBI5511-25MG | Yes | 25 MG | $360.00 |
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Description
Product Details
Formal Name: 4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoic acid
Alternate Names: CD336; NSC 608001; Ro 40-6055
Molecular Formula: C22H25NO3
Formula Weight: 351.40
CAS Number: 102121-60-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (35 mg/ml); or Ethanol (18 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Retinoid RARα agonist
Functions
A retinoic acid analog acting as a RARα agonist (Kd = 8 nM). Induces or blocks differentiation depending on cell type and environment. In combination with CHIR-99021 it induces differentiation of human induced pluripotent stem cells (iPSCs) into intermediate mesoderm (80% induction rate in 5 days) capable of forming kidney structures. AM-580 exhibits anti-angiogenic activity in vivo, and induces differentiation of acute promyelocytic leukemia cells.
Application Procedures
First dissolved in DMSO (35 mg/ml); or Ethanol (18 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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