AG-1478, EGFR kinase inhibitor (TBI2117)
$90.00 – $270.00
EGFR kinase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2117-5MG | Yes | 5 MG | $90.00 | |||
TBI2117-25MG | Yes | 25 MG | $270.00 |
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Description
Product Details
Formal Name: N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine, free base
Molecular Formula: C16H14ClN3O2
Formula Weight: 315.76
CAS Number: 175178-82-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming).
Storage: -20°C
Stability: ≥ 1 year.
Applications
EGFR kinase inhibitor
Functions
Potent and selective inhibitor of the EGFR kinase IC50 = 3 nM. Inhibits proliferation of a variety human cancer cell lines. Reduces pulmonary fibrosis in a rat model. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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