Ac-Leu-Leu-Methional (ALLM), Calpain inhibitor (TBI1349)
$108.00 – $315.00
Calpain inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1349-5MG | Yes | 5 MG | $108.00 | |||
TBI1349-25MG | Yes | 25 MG | $315.00 |
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Description
Product Details
Formal Name: N-Acetyl-Leu-Leu-Methional
Alternate Names: Ac-LLM-CHO; Calpain inhibitor II
Molecular Formula: C19H35N3O4S
Formula Weight: 401.56
CAS Number: 136632-32-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Calpain inhibitor
Functions
Cell-permeable, peptide aldehyde inhibitor of calpain (calpain I, Ki = 120 nM, calpain II, Ki = 230 nM) and other neutral cysteine proteases. Potent inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM). Weak inhibitor of the chymotrypsin-like activity of the proteasome. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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