7,8-Dihydroxyflavone, TrkB agonist/neurotrophic (TBI1174)
$81.00 – $270.00
TrkB agonist/neurotrophic
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1174-100MG | Yes | 100 MG | $81.00 | |||
TBI1174-500MG | Yes | 500 MG | $270.00 |
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Description
Product Details
Formal Name: 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
Molecular Formula: C15H10O4
Formula Weight: 254.25
CAS Number: 38183-03-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 6 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
TrkB agonist/neurotrophic
Functions
A selective TrkB agonist (Kd=320 nM) with potent neurotrophic activity. Significantly improves motor deficits, ameliorates brain atrophy and extends survival in the well-characterized N171-82Q Huntington’s disease mouse model. Post-traumatic brain injury-treatment promotes neurogenesis in the hippocampus in a mouse model. Improves motor performance and motor neuronal survival in an ALS mouse model.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 6 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 week.
Additional information
SIZE (mg) | 500 MG, 100 MG |
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