5a,6a-Epoxycholesterol, LXR ligand (TBI4545)

Description

Product Details

Formal Name: Cholestan-5α,6α-epoxy-3β-ol

Molecular Formula: C₂₇H₄₆O₂

Formula Weight: 402.65

CAS Number: 1250-95-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

 

Applications

LXR ligand

 

Functions

5α,6α-Epoxycholesterol is a naturally occurring metabolite of cholesterol.  It is a major oxysterol found in processed food and has been implicated in atherosclerosis. 5α,6α-Epoxycholesterol has been found to be an endogenous ligand for LXR (EC50 = 76 nM).

 

Application Procedures

First dissolved in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Additional information

SIZE (mg)	25 MG, 100 MG

TBI4545_5a,6a-Epoxycholesterol