25-Hydroxycholesterol, Cholesterol metabolite (TBI4539)
$54.00 – $189.00
Cholesterol metabolite
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4539-5MG | Yes | 5 MG | $54.00 | |||
TBI4539-25MG | Yes | 25 MG | $189.00 |
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Description
Product Details
Formal Name: 5-Cholesten-3β, 25-diol
Molecular Formula: C27H46O2
Formula Weight: 402.66
CAS Number: 2140-46-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO or in Ethanol.
Storage: -20°C
Stability: ≥ 1 year.
Applications
Cholesterol metabolite
Functions
Metabolite resulting from the action of cholesterol 25-hydroxylase on cholesterol. However, since cholesterol 25-hydroxylase knock-out mice still have significant levels of 25-hydroxycholesterol there must be alternate pathways of generation that have yet to be determined. Likewise, the biological role of 25-hydroxycholesterol remains somewhat unclear. 25-Hydroxycholesterol is frequently mentioned as an important regulator of cholesterol metabolism, but apparently normal cholesterol regulation in organisms with both high and low levels of the compound make this association unclear. More recent reports have linked 25-hydroxycholesterol and one of it’s metabolites to immunoregulatory roles, but more information is needed before it’s clear if that is indeed a primary role for the compound.
Application Procedures
First dissolved in DMSO or in Ethanol, then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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