1,4-DPCA, Prolyl hydroxylase inhibitor (TBI2956)
$76.00 – $288.00
Prolyl hydroxylase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI2956-5MG | Yes | 5 MG | $76.00 | |||
TBI2956-25MG | Yes | 25 MG | $288.00 |
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Description
Product Details
Formal Name: 1,4-Dihydrophenonthrolin-4-one-3-carboxylic acid
Molecular Formula: C13H8N2O3
Formula Weight: 240.22
CAS Number: 331830-20-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 15 mg/ml with warming)
Storage: RT
Stability: ≥ 2 years.
Applications
Prolyl hydroxylase inhibitor
Functions
Potent inhibitor of prolyl 4-hydroxylase (IC50=2-4 μM). Inhibits collagen deposition via inhibition of collagen proline hydroxylation. Subcutaneous injection of a 1,4-DPCA containing hydrogel into Swiss Webster mice that do not show a regenerative phenotype increased expression of HIF1α over 5 days. Multiple injections led to regenerative wound healing after ear hole punch injury.
Application Procedures
First dissolved in DMSO (up to 15 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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