10058-F4, Myc inhibitor (TBI1466)
$97.00 – $360.00
Myc inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1466-5MG | Yes | 5 MG | $97.00 | |||
TBI1466-25MG | Yes | 25 MG | $360.00 |
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Description
Product Details
Formal Name: 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
Molecular Formula: C12H11NOS2
Formula Weight: 249.36
CAS Number: 403811-55-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 20 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
Myc inhibitor
Functions
Effectively disables c-Myc by inhibiting the c-Myc-Max associationn and function. It prevents the growth of fibroblasts in a c-Myc-dependent manner. Downregulates human telomerase reverse transcriptase and enhances chemosensitivity in human hepatocellular carcinoma cells. Induces cell cycle arrest, apoptosis and myeloid differentiation in human acute myeloid leukemia. Inhibits the MYCN/Max interaction leading to cell cycle arrest, apoptosis and neuronal differentiation in MYCN-amplified neuroblastoma cells.
Application Procedures
First dissolved in DMSO (up to 60 mg/ml) or in Ethanol (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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