Tribio InVivoMAb Anti-Human FAP & CD3E Bispecific Antibody (TBS10494)

Description

Description: Tribio InVivoMAb Anti-Human FAP & CD3E Bispecific Antibody is a mouse research bispecific antibody that targets FAP (fibroblast activation protein) and CD3ε to redirect and activate T cells against FAP-expressing cancer-associated fibroblasts in the tumor microenvironment. It is mainly used in preclinical cancer immunotherapy studies to evaluate T-cell–engaging strategies targeting tumor stroma.

Applications: FuncS

Species reactivity: Human

Host species: Human

Target: Bispecific, Surface-expressed protease, Gelatine degradation protease FAP, Integral membrane serine protease, Dipeptidyl peptidase FAP, Seprase, FAP, Post-proline cleaving enzyme, APCE, SIMP, FAPalpha, 170 kDa melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Serine integral membrane protease, Prolyl endopeptidase FAP, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain

Isotype: IgG1, kappa

Accession/UniProt: Q12884 & P07766

Concentration: 3 mg/ml

Purity: >95%

Formulation: Liquid

Storage buffer: 0.01M PBS, pH 7.4

Purification: Protein A/G purified from cell culture supernatant.

Clonality: Monoclonal

Storage: Avoid repeated freeze-thaw cycles. -20°C for 12 months; -80°C for long-term storage.

Research use only.

Additional information