InVivoMAb Anti-Human IGF1 Antibody (TBS10343)
$489.00 – $2,399.00
Target: IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C.
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBS10343-0.5MG | Yes | 0.5 MG | $489.00 | |||
| TBS10343-1MG | Yes | 1 MG | $719.00 | |||
| TBS10343-5MG | Yes | 5 MG | $2,399.00 |
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Description
InVivoMAb Anti-Human IGF-1 antibody is a monoclonal antibody designed to specifically bind and neutralize human insulin-like growth factor-1 (IGF-1), a key growth factor involved in cell proliferation, survival, and tumor progression. By blocking IGF-1 signaling, this antibody is widely used in in vivo and translational research to inhibit IGF-1–mediated cancer cell growth and proliferation, investigate IGF-driven oncogenic pathways, and evaluate therapeutic strategies targeting the IGF axis in cancer and other IGF-1–related diseases.
Synonyms: Anti-Human IGF-1 monoclonal antibody, Anti-IGF-1 antibody, IGF-1 neutralizing antibody, IGF-1–specific mAb, In-vivo anti-IGF-1 antibody, Neutralizing anti-IGF-1 mAb.
Product Details
| Applications: | ELISA, FCM, Neutralization |
| Species reactivity: | Human |
| Host: | Human |
| Isotype: | IgG1, lambda |
| Target: | IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C. |
| Uniprot: | P05019 |
| Concentration: | 3 mg/ml |
| Purity: | >95% |
| Formulation: | Liquid |
| Storage buffer: | 0.01M PBS, pH 7.4. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Clonality: | Monoclonal |
| Storage: | Store -20°C up to 12 months, and -80°C for long term. Avoid repeated freeze-thaw cycles. |
Data Image
Fig. 1. SDS-PAGE for InVivoMAb Anti-Human IGF1.
MW: Molecular Weight (kDa) Marker.
R: Reducing conditions.
NR: Non-Reducing conditions.
Fig. 2. SEC-HPLC detection for InVivoMAb Anti-Human IGF1
Fig. 3. Flow-cytometry using anti-human IGF2 antibody. HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human IGF2 antibody monoclonal antibody (Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody and cells analyzed on a NovoCyte Flow Cytometer.
Fig. 4. Flow-cytometry using anti-human IGF1 antibody. Human Jurkat cell line were stained with an irrelevant antibody (Blue Histogram) or an anti-human IGF1 antibody monoclonal antibody (Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody and cells analyzed on a NovoCyte Flow Cytometer.
Fig. 5. Flow-cytometry using anti-human IGF2 antibody. A549 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human IGF2 antibody monoclonal antibody (Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody and cells analysed on a NovoCyte Flow Cytometer.
Fig. 6. Flow-cytometry using anti-human IGF1 antibody. HeLa cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human IGF1 antibody monoclonal antibody (Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody and cells analysed on a NovoCyte Flow Cytometer.
Research use only.
Additional information
| SIZE (mg) | 1 MG, 5 MG, 0.5 MG |
|---|
Datasheet:
TBS10343 InVivoMAb Anti-Human IGF1_Datasheet
MSDS:
TBS10343_InVivoMAb Anti-Human IGF1 Antibody_MSDS
Research use only.
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