Recombinant Tryptase Activity
Recombinant Tryptase α/β1 Activity Introduction: Tryptase is the most abundant preformed granular enzyme found in all human mast cells and is frequently used as a marker for mast cell activation. Tryptase has α, β, γ, and δ isoforms. Of the four isoforms of tryptase, β-tryptase and to a lesser extent α-tryptase, are considered the most biologically significant. The γ and δ forms of tryptase are believed to have little, if any, catalytic activity. α-tryptase and β1-tryptase alleles are co-allelic at the TPSAB1...