Geranylgeranoic acid, Bioactive Isoprenoid (TBI3337)

Description

Product Details

Formal Name: all trans-3,7,11-15-Tetramethyl-2,6,10,14-hexadecatetraenoic acid

Alternate Names: GGA

Molecular Formula: C₂₀H₃₂O₂

Formula Weight: 304.5

CAS Number: 35750-48-2

Purity: >96%

Formulation: Liquid

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

Bioactive Isoprenoid

Functions

An acyclic retinoid that is found naturally occurring in several traditional herbal medicines. Like many retinoids, geranylgeranoic acid plays a role in bone formation. It has been demonstrated to induce osteoblast differentiation and to inhibit osteoclast formation both in vitro and in vivo. It has been shown to induce apoptosis in various cell lines including HuH-7, PLC/PRF-5 and MLE-10. Induces unfolded protein response in human hepatoma cells. It effectively inhibits methicillin-resistant Staphylococcus aureus adhesion to keratin, fibronectin, fibrinogen, and immunoglobulins offering a potentially new treatment for a difficult to treat bacteria.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Research use only.

Additional information

Datasheet:

TBI3337_Geranylgeranoic acid_Datasheet

MSDS:

TBI3337_Geranylgeranoic acid_MSDS

Research use only.