Hinokitiol, Iron chelator; antioxidant (TBI2211)
$94.00 – $315.00
Iron chelator; antioxidant
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2211-50MG | Yes | 50 MG | $94.00 | |||
TBI2211-250MG | Yes | 250 MG | $315.00 |
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Description
Product Details
Formal Name: β-Thujaplicin, 2-Hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one
Molecular Formula: C10H12O2
Formula Weight: 164.20
CAS Number: 499-44-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
Iron chelator; antioxidant
Functions
Monoterpene natural product first isolated from the western red cedar, identified as a metal chelator and ionophore with activity against microbial growth. Inhibits mushroom tyrosinase (IC50 diphonolase activity = 0.21 μM) and platelet 12-lipoxygenase (IC50 = 100 nM). Protects against prion-induced neurotoxicity by inducing autophagy via HIF-1α activation. Causes G1 arrest, autophagy, and EGF-induced migration in HeLa cells.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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