Ibandronate, Farnesyl pyrophosphate synthase inhibitor (TBI4630)
$54.00 – $180.00
Farnesyl pyrophosphate synthase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4630-50MG | Yes | 50 MG | $54.00 | |||
TBI4630-250MG | Yes | 250 MG | $180.00 |
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Description
Product Details
Formal Name: (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid, sodium monohydrate
Alternate Names: BM-21.0955
Molecular Formula: C9H22NNaO7P2 • H2O
Formula Weight: 359.23
CAS Number: 138926-19-9
Purity: >98%
Formulation: powder
Solubility: Soluble in water (up to at least 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Farnesyl pyrophosphate synthase inhibitor
Functions
Clinically useful bisphosphonate for prevention and treatment of osteoporosis, and skeletal fractures in patients with cancer. Potent inhibitor of farnesyl pyrophosphate synthase (IC50 = 20 nM) and strongly binds hydroxyapatite (1/Kd = 2.4 µM), interfering with crystal growth, slowing resorption, and thereby maintaining bone strength.
Application Procedures
First dissolved in water (up to at least 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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