Cepharanthine, Antiinflammatory natural product; Antioxidant (TBI5074)
$63.00 – $252.00
Antiinflammatory natural product; Antioxidant
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI5074-50MG | Yes | 50 MG | $63.00 | |||
TBI5074-250MG | Yes | 250 MG | $252.00 |
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Description
Product Details
Formal Name: 2,3,13,14,14aS,15,26,26aR-octahydro-22,30-dimethoxy-1,14-dimethyl-1H-4,6:16,19-dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2’,3’:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline
Alternate Names: O-Methylcepharanoline; NSC 623442
Molecular Formula: C37H38N2O6
Formula Weight: 606.70
CAS Number: 481-49-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to at least 50 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Antiinflammatory natural product; Antioxidant
Functions
A naturally occurring alkaloid from Stephania cepharantha Hayata which possesses a number of pharmacological activities. Attenuates LPS-induced expression of TNF-a, IL-6 and IL-1b in macrophages and inhibits NF-kB activation. Induces mitophagy possibly by acting at GPR30 in hepatocellular carcinoma. Inhibits autophagosome-lysosome fusion and autophagy by downregulation of MYO1C an actin-based motor protein. Potently inhibits replication of SARS CoV-2 and homologous viruses.
Application Procedures
First dissolved in DMSO (up to at least 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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