LM22A-4, TrkB small molecule agonist (TBI1405)
$90.00 – $396.00
TrkB small molecule agonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1405-5MG | Yes | 5 MG | $90.00 | |||
TBI1405-25MG | Yes | 25 MG | $396.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: N,N’N’ Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide
Molecular Formula: C15H21N3O6
Formula Weight: 339.35
CAS Number: 37988-18-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
TrkB small molecule agonist
Functions
Small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administraton, it caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats. Improves respiratory function in a mouse models of Rett syndrome.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml), or in Water (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “LM22A-4, TrkB small molecule agonist (TBI1405)”
You must be logged in to post a review.
Reviews
There are no reviews yet.