BD1047 dihydrobromide, Selective sigma-1 antagonist (TBI4210)
$81.00 – $333.00
Selective sigma-1 antagonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4210-5MG | Yes | 5 MG | $81.00 | |||
TBI4210-25MG | Yes | 25 MG | $333.00 |
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Description
Product Details
Formal Name: N-[2-(3,4 Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide
Molecular Formula: C13H20Cl2N2·2HBr
Formula Weight: 437.04
CAS Number: 138356-21-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Selective sigma-1 antagonist
Functions
BD1047 is a potent and selective sigma-1 antagonist (IC50’s: sigma1 = 0.93nM, sigma2 = 47nM). Pretreatment of mice with BD1047 reduced convulsions, lethality, and locomotor activity induced by cocaine. BD1047 attenuated high fat diet-induced peripheral neuropathy in mice. BD1047 displayed antinociceptive effects in several rodent pain models. It also inhibits the beta-adrenoreceptor (IC50 = 145 nM).
Application Procedures
First dissolved in DMSO (up to 20 mg/ml) or in Water (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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