GRL-0667, SARS-CoV-2 papain-like protease (PLpro, Nsp3) inhibitor (TBI4963)
$171.00 – $666.00
SARS-CoV-2 papain-like protease (PLpro, Nsp3) inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4963-5MG | Yes | 5 MG | $171.00 | |||
TBI4963-25MG | Yes | 25 MG | $666.00 |
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Description
Product Details
Formal Name: 1-[(R)-1-(1-Naphthyl)ethyl)]-4-[3,4-(methylenedioxy)benzylamino]carbonylpiperidine
Molecular Formula: C26H28N2O3
Formula Weight: 416.50
CAS Number: 1234195-91-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or Ethanol (up to 15 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
SARS-CoV-2 papain-like protease (PLpro, Nsp3) inhibitor
Functions
GRL-0667 is a potent (IC50 = 320 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL-0667 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 9.1 µM).
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or Ethanol (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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