Isopimaric acid, Potassium channel activator (TBI5487)
$108.00 – $432.00
Potassium channel activator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI5487-5MG | Yes | 5 MG | $108.00 | |||
TBI5487-25MG | Yes | 25 MG | $432.00 |
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Description
Product Details
Formal Name: (1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylic acid
Alternate Names: ISO
Molecular Formula: C20H30O2
Formula Weight: 302.50
CAS Number: 5835-26-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (40 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Potassium channel activator
Functions
Terpenoid acid that activates BK (voltage-gated potassium) channels when used at 10 µM in HEK293 cells. Improves spatial and non-spatial memory in Alzheimer’s mouse model, and significantly improves motor function in a rat spinal cord injury model. Reduces hyperactivity of spontaneously active auditory networks, EC50=7.8 μM.
Application Procedures
First dissolved in DMSO (40 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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