TRO 19622 (Olesoxime), Neurotrophic agent (TBI3230)
$99.00 – $360.00
Neurotrophic agent
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3230-5MG | Yes | 5 MG | $99.00 | |||
TBI3230-25MG | Yes | 25 MG | $360.00 |
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Description
Product Details
Formal Name: Cholest-4-en-3-one oxime
Alternate Names: Olesoxime
Molecular Formula: C27H45NO
Formula Weight: 399.65
CAS Number: 22033-87-0
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Neurotrophic agent
Functions
Neuroregenerative and neuroprotective agent acting at components of the mitochondrial permeability transition pore (MPTP). Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in mice. Reduces ROS and NLRP3 inflammasome activation in a mouse model of intracerebral hemorrhage. Inhibits MPTP opening and protects neurons from apoptosis. Induces oligodendrocyte maturation in culture and promotes myelin regeneration in vivo in a rodent model.
Application Procedures
First dissolved in DMSO (up to 20 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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