HA-100 2HCl, Multi-kinase inhibitor (TBI1609)

Description

Product Details

Formal Name: 5-(1-Piperazinylsulfonyl)isoquinoline dihydrochloride

Molecular Formula: C₁₃H₁₅N₃O₂S  • 2HCl

Formula Weight: 350.30

CAS Number: 84468-24-6

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml) or in water (up to 40 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

 

Applications

Multi-kinase inhibitor

 

Functions

Inhibits the following kinases  PKG (IC50=4 mM), PKA (IC50=8 mM), PKC (IC50=12 mM)1. Increases human fibroblast reprogramming efficiency with PD0325901, CHIR99021, A83-01 and hLIF. Improves single cell survival and supports high cloning efficiency in human pluripotent stem cells.

 

Application Procedures

First dissolved in DMSO (up to 30 mg/ml) or in water (up to 40 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.

Additional information

SIZE (mg)	25 MG, 5 MG

Datasheet:

TBI1609_HA-100 2HCl

MSDS:

TBI1609_HA-100 2HCl_MSDS_2024