PK-11195, Mitochondrial BZD receptor ligand (TBI2221)
$63.00 – $234.00
Mitochondrial BZD receptor ligand
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2221-5MG | Yes | 5 MG | $63.00 | |||
TBI2221-25MG | Yes | 25 MG | $234.00 |
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Description
Product Details
Formal Name: 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
Molecular Formula: C21H21ClN2O
Formula Weight: 352.86
CAS Number: 85532-75-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
Mitochondrial BZD receptor ligand
Functions
PK-11195 is a selective and potent peripheral benzodiazepine receptor, PBR (or TSPO, translocator protein) antagonist. It has been shown to chemosensitize tumor cells to a variety of chemotherapeutic agents via PBR-independent pathways. PK11195 is also able to induce apoptosis in a variety of cell lines.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored under nitrogen or argon at -20° for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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