GSK2879552, Lysine Demethylase inhibitor (TBI4020)
$144.00 – $477.00
Lysine Demethylase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4020-5MG | Yes | 5 MG | $144.00 | |||
TBI4020-25MG | Yes | 25 MG | $477.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: 4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride
Molecular Formula: C23H28N2O2 ·2HCl
Formula Weight: 437.40
CAS Number: 1401966-69-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) and in Water (up to at least 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Lysine Demethylase inhibitor
Functions
GSK289552 is potent, selective, and irreversible inhibitor of Lysine Demethylase 1 (LSD1) via covalent modification of the LSD1 cofactor FAD (Ki = 1.7 µM). It is selective for LSD1 over the closely related LSD2, MAO-A, MAO-B, and the FAD dependent enzymes D-amino acid oxidase and glutathione reductase. Tested against a panel of 165 cancer cell lines, GSK2879552 inhibited the proliferation of 9 small cell lung carcinoma lines and 20 AML cell lines.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) and in Water (up to at least 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “GSK2879552, Lysine Demethylase inhibitor (TBI4020)”
You must be logged in to post a review.
Reviews
There are no reviews yet.